Tranquilizer 2863
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A tranquilizer is a drug that acts on the central nervous system and is used to calm, decrease anxiety, or help a person to sleep. Often called depressants because they suppress the central nervous system and slow the body down, they are used to treat mental illness as well as common anxiety and sleeplessness. Available only by prescription, they can cause dependence and certain ones can easily be abused.

Major and minor tranquilizers

There are two types or classes of tranquilizers: major tranquilizers and minor tranquilizers. The former are antipsychotic drugs and the latter are considered antianxiety drugs. Antipsychotic drugs are used to treat patients with a severe mental illness, like schizophrenia (pronounced skit-zo-FREH-nee-uh). Antianxiety drugs are given to patients with emotional problems, like anxiety. Both types of tranquilizers were first introduced in the 1950s. At the time, they revolutionized psychiatry for they seemed to offer physicians a way to manage psychoses (pronounced sy-KOH-sees), which are severe forms of mental illness, and to make their patients emotionally calm and quiet. They also seemed to offer an alternative to people simply trying to cope or put up with the everyday anxieties, tension, and sleeplessness that many experience in their normal lives.

Major tranquilizers for psychoses

The major tranquilizers were first developed in the very early 1950s when scientists discovered that the organic compound called phenothiazine (pronounced fee-no-THY-uh-zeen) had a strong sedative effect, meaning it calmed or relaxed the person taking it. In 1952, a phenothiazine derivative called chlorpromazine (pronounced klor-PRO-muhzeen) was seen to make highly agitated patients quiet and calm without making them unconscious. However, it also made them much less aware mentally, as they seemed to have little or no interest in anything going on around them. These calming effects led doctors to begin giving this new drug (whose trade name was Thorazine) to severely disturbed, psychotic patients, since for the first time, science had found a drug that specifically targeted the central nervous system.

Words to Know

Anxiety: A feeling of uneasiness and distress about something in the future.

Insomnia: Inability to go to sleep or stay asleep.

Psychosis: A major psychiatric disorder characterized by the inability to tell what is real from what is not real.

Schizophrenia: A serious mental illness characterized by isolation from others and thought and emotional disturbances.

About the same time, another compound called reserpine became useful as a major tranquilizer. It was found to reduce the delusions and hallucinations of schizophrenics. However, it eventually was replaced by another class of drugs since it had several physical side effects. Although antipsychotic drugs or major tranquilizers have side effects—such as increased heart rate, dry mouth, blurred vision, and constipation—they are not addictive and patients seldom build up a tolerance for them. Since they do not give the user any of the good feelings that stimulants do (instead they cause drowsiness), they do not lend themselves to recreational use. They will not make a person feel "high."

Minor tranquilizers for anxiety

Minor tranquilizers are quite different, however, and although these antianxiety drugs are called "minor," there is in fact nothing minor or mild about these drugs. Nor is there anything minor about their effects or their potential for abuse. This class of drugs is the most common type of drug today. More prescriptions are written for these compounds than for any other type of drugs. Minor tranquilizers include the well-known brand names of Valium, Librium, Xanax, and Ativan. Unlike major tranquilizers, which are used by doctors to try and manage severe psychiatric illnesses, minor tranquilizers are given fairly liberally by doctors to patients who complain about anxiety, depression, and sleep disorders. Minor tranquilizers work by reducing tension without heavily sedating the patient. Although they relax tense muscles, they produce less sleepiness during the day than major tranquilizers, although at night they do help with sleep.

Though they should be taken in prescribed doses for short periods of time, many people take these minor tranquilizers regularly, and they can cause dependence and tolerance. This means that the patient may experience unpleasant withdrawal symptoms if they suddenly stop taking them, and that they eventually need to take larger doses to maintain a feeling of well-being. Minor tranquilizers are the most widely abused drug in the United States and are regularly involved in suicide attempts and accidental overdoses. Called "downers" on the street, they can give a feeling of calm and relaxation (some say a "floating" sensation) that can, however, turn into more serious and unpleasant side effects. Over-use of downers can make people hostile and aggressive, and leave them with blurred vision, memory loss, disorganized thinking, headaches, and depression.

Not a cure

Whether major or minor tranquilizers, these two classes of drugs are not a cure for any of the conditions they treat. They are given by doctors to relieve symptoms that are associated with other problems. Neither type of drug should be taken with alcohol, as both are depressants and can therefore compound or exaggerate the effect of the other. People who take tranquilizers also should not drive a car or operate anything mechanical for several hours after taking the pills, since they interfere with the control of a person's movements. Although technically there are major and minor tranquilizers, the word "tranquilizer" has commonly come to refer only to the minor class of drugs that treat anxiety and insomnia—probably because they are the most frequently prescribed type of drug in the world.

[ See also Psychosis ; Schizophrenia ]

Also read article about Tranquilizer from Wikipedia

User Contributions:

Sam Walker
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May 17, 2006 @ 10:10 am
I feel I am becoming addicted to Ativan. Are there any herbal
medicines that might give me the same results.....or could you advise me how to "get off" Ativan? I tried simply not taking it but the withdrawal symptoms were very strong. Any advice you can give me will be greatly appreciated.

Yours respectfully.
Sam Walker
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Feb 1, 2010 @ 11:11 am
is there ay other medication available if dome one dont want to use the Tranquilizers.. dr prescribesd me for the same but i know this can left me addicted
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Aug 10, 2010 @ 9:09 am
i regularly take xanax and is my primary tranq i use for panic attacks and to help me sleep. but there comes a time when i dont have any for some reason, i can get Valerian, which is a natural tranquilizer/sedative that you can get over the counter. its only 4 bucks at walmart and u get like 100 per bottle! so its win/win for me. plus, i learned that Valerian has little to no side effects! but even so, xanax has always been my favorite for years. (ive taken ativan on and off, and klonopin at one point). none of them amount to what xanax can do for me, even if it IS temporary. NO drug is one size fits all.
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Aug 28, 2010 @ 3:15 pm
I have been on both the major and minor tranquilizers. To say the major tranquilizers can't be abused or addictive is short sighted at best. People do build tolerance to them and have withdrawal coming off of them. Also, the major Tranquilizers have much worse side effects, the danger of tartive dyskensia and diabetes. They are passed out like candy along with antidepressants that are also addictive and have withdrawal effects. The difference between the AD's and AP's vs. the benzo's is that the benzo's actually make people feel better with less side effects, they are cheaper in price as well. It's ashame psychiatry is so benzo phobic and having to put people on much more dangerous meds that don't work as well.
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Sep 6, 2010 @ 6:06 am
what are the proper ways of handling, storing, and disposing of tranquilizer?
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Mar 3, 2011 @ 3:03 am
this information is searched for applied chemistry assignment good afternoon
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Sep 21, 2011 @ 3:15 pm
I have been reading about minor tranquilizers for anxiety and was wondering. A person with high blood pressure would be prescribed tranquilizers, would it also help with lowering blood pressure? I have been under a lot of stress along with anxiety and sometimes uncontrollable anger, I have been thinking a lot about asking my doctor if she would prescribe a minor tranquilizer to me.
Tranquilizer Reasearcher
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Dec 7, 2011 @ 9:09 am
Are traquilizers addictive? I think that it might be, but I do not know. Please tell me if it is or not.
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Aug 17, 2012 @ 8:20 pm
My brother has started taking tranquilizers, anti anxiety tabs and antidepressants all together prescribed by his gp and he seems worse for it, blurred vision, confused feeling, sleeping 16 hrs a night, shakes and very high blood pressure. Also he is having vivid nightmares, i am so worried about him and don't know where to turn :(
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Nov 11, 2014 @ 3:15 pm
What are the side effects of tranquilizer use?

Many users report lethargy, drowsiness, and dizziness after taking tranquilizers. Decreased motivation, irritability, nausea, headaches, skin rashes, impaired sexual functioning, menstrual irregularities, tremors, loss of appetite, or increased appetite, lethargy and over sedation, and vivid or disturbing dreams are all possible side effects of tranquilizer use. With regular use, tranquilizers can create psychological and physical dependence similar to that of barbiturates
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Sep 2, 2015 @ 1:01 am
im on clonazepam 1 mg and celexa 40 mg now at first they put me on just celexa for months it did not work then they gave me clonazepam starting at half of half one mg and it is a life saver iv been on it for 5 years now and im very happy ,benzos are very good for anxiety/panic issues short or long term.
thomas vanleuven
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Apr 13, 2016 @ 8:20 pm
Hello everyone, i tried every adaptegen herb i could find for sleep and anxeity but none has helped. Could someone tell me about a natural downer or deppressant? I have tried hops,lemon balm, valerian, ashwaganda,5htp,st johns wort, ginko bilova,rodlia,chamomile,focus factor worked for a year. Also tried vitamins minerals like b vitamins and magnseium. They didnt work. I tried gaba,amino acids didnt work. Does anyone have any experiance or any success in this area? Thanks. Thomasv
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Jun 6, 2016 @ 4:16 pm
, Has anyone ever been on tranquilzerS for 20 or more years ? and was it a prescribed dose ? I have anxiety disorder , and want to get off , but not by detoz and I don't know how their are a lot of methods I can share with someone , but is anyone in my position , took 2mg for 10 years , then went to 3 mgs for another 10 im pretty sure its mostly dependecy , someone email me if been on for long term ise like this, or anyone that had been on long term use and got off using some method Robert orena
Fred Renaud
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Mar 12, 2017 @ 4:04 am
Ya I've been on olanzapine (major tranquiliser) for about 8 months I'm off them and use them on occasions where there is a lot of people because of my panic attacks caused by social anxiaty. I am bot yet addicted to the drug, but i can start to feel minor withdrawal. For the withdrawal id say its all about the way you think. First, know and understand that you can function well without the drug. After that, learn your automatic thoughts and conquer them, channel them into motivating positive thought. Also, focus on breathing deep a lot when you feel a bit of tension, especially in the chest. You should be golden, you'll be way happier and proud of yourself when your finally anxiety free and mastered your thought process. Talk to your therapist about all of the above and have a kick ass life bud.

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